Which of the Following Conditions is Most Apt to Decrease

Question

Which of the following conditions is most apt to decrease glomerular filtration rate (GFR)?
A) Overhydration
B) Hypotension
C) Administration of a diuretic for the treatment of edema
D) Water intoxication

Accepted Answer

Hypotension, or low blood pressure, can decrease the perfusion pressure in the glomerulus and therefore decrease GFR. Overhydration and water intoxication may increase GFR temporarily. Administration of a diuretic may initially decrease GFR but can also lead to increased GFR over time as fluid is lost from the body.