The Central Chemoreceptors are Primarily Sensitive to Blood Levels Of

Question

The central chemoreceptors are primarily sensitive to blood levels of A) oxygen. B) carbon dioxide and [H⁺]. C) sodium. D) potassium.

Accepted Answer

The central chemoreceptors, located in the medulla oblongata of the brain, are primarily sensitive to changes in blood levels of carbon dioxide (CO2) and the resulting increase in hydrogen ions (H+), which combine to form bicarbonate (HCO3-). An increase in CO2 leads to an increase in H+ and HCO3-, resulting in acidosis, which is detected by the central chemoreceptors and results in an increase in ventilation to remove excess CO2 and decrease H+ levels. Oxygen levels also play a role in ventilation, but the peripheral chemoreceptors located in the carotid and aortic bodies are primarily responsible for monitoring blood oxygen levels. Sodium and potassium are not directly involved in the regulation of ventilation by the central chemoreceptors.