Activation of the Muscarinic Receptors by Acetylcholine

Question

Activation of the muscarinic receptors by acetylcholine
A) increases myocardial contractile force.
B) causes a (+) chronotropic effect.
C) increases cardiac output.
D) slows heart rate.

Accepted Answer

Activation of muscarinic receptors by acetylcholine slows heart rate, due to the activation of the parasympathetic nervous system. This is also known as the negative chronotropic effect.