Which of the Following Mom-Baby Combinations is Most Apt to Induce

Question

Which of the following mom-baby combinations is most apt to induce erythroblastosis fetalis?
A) Mom O(+), baby O(+)
B) Mom AB(+), baby AB(-)
C) Mom AB(-). Baby O(-)
D) Mom AB(-), baby O(+)

Accepted Answer

Erythroblastosis fetalis or hemolytic disease of the newborn occurs when the mother's blood type is Rh-negative, and the baby's blood type is Rh-positive. Option D is the only combination where the mother is Rh-negative (AB-) and the baby is Rh-positive (O+), which can lead to the development of antibodies by the mother's immune system against the baby's Rh antigens, causing hemolysis of the baby's red blood cells.