The Reaction of -COOH and -NH₂

Question

The reaction of -COOH and -NH₂
A) forms urea.
B) creates a peptide bond.
C) forms glycogen.
D) forms a ketone body.

Accepted Answer

When a carboxylic acid (-COOH) and an amine (-NH2) react together, they undergo a condensation reaction, where a molecule of water is eliminated, resulting in the formation of an amide bond (-CONH-). This amide bond is the basis for peptide bond formation in proteins, making choice B the correct answer. Urea (A) is formed by the reaction of ammonia and carbon dioxide, while glycogen (C) is a complex carbohydrate polymer made by the body. Ketone bodies (D) are formed as a result of incomplete fatty acid metabolism in the liver.