What is the Drawback of Live Attenuated Vaccines

Question

What is the drawback of live attenuated vaccines?
A) They require more secondary reimmunizations than other vaccines.
B) They are not effective in adults.
C) They do NOT provide a long-lasting secondary immune response.
D) They can cause disease in some immunocompromised individuals.

Accepted Answer

The drawback of live attenuated vaccines is that they can cause disease in some immunocompromised individuals, such as those with HIV or undergoing chemotherapy. This is because the weakened virus used in the vaccine may still be able to replicate and cause disease in individuals with weakened immune systems.