TCRs Recognize Epitopes Only After the Immunogens Have Been Partially

Question

TCRs recognize epitopes only after the immunogens have been partially degraded.

Accepted Answer

TCRs recognize epitopes presented on MHC molecules only after the antigenic protein has been partially processed and degraded by antigen presenting cells. This allows for the presentation of peptide fragments on the MHC molecule, which can then be recognized by the TCR.