________ Ensures That Each B Cell Produces Only One Immunoglobulin

Question

________ ensures that each B cell produces only one immunoglobulin.
A) Self-activation
B) Allelic exclusion
C) MHC interaction
D) Clonal deletion

Accepted Answer

Allelic exclusion ensures that each B cell produces only one type of immunoglobulin by shutting off expression of one of the two immunoglobulin gene alleles during development. This allows for diversity in the B cell repertoire and prevents the production of self-reactive antibodies. Self-activation, MHC interaction, and clonal deletion are all different mechanisms involved in the regulation of the immune response, but they do not specifically ensure that each B cell produces only one immunoglobulin.