The Invariant Amino Acids in Each Peptide Motif Bound by MHC

Question

The invariant amino acids in each peptide motif bound by MHC proteins are called
A) anchor residues.
B) MHC peptides.
C) antigen-binding immunoglobulins.
D) TCR peptides.

Accepted Answer

Anchor residues are invariant amino acids that help to hold the peptide in the correct position for binding to the MHC protein. These anchor residues are important for determining the specificity of the peptide-MHC complex for binding to T cell receptors (TCRs). The other answer choices are not accurate descriptions of this concept.