Clonal Anergy is a State Of

Question

Clonal anergy is a state of
A) antibody production.
B) high energy.
C) unresponsiveness.
D) high energy and antibody production.

Accepted Answer

Clonal anergy is a state of unresponsiveness, in which T or B lymphocytes do not respond to a specific antigen. It occurs when the lymphocyte receptor binds to its antigen without receiving proper activation signals, leading to a lack of proliferation and cytokine production, and resulting in immune tolerance. Therefore, option C is the best choice. Options A and D are incorrect since clonal anergy does not involve antibody production. Option B is also incorrect since high energy is not related to clonal anergy.