Interaction of a PAMP with a TLR Triggers Transmembrane Signal

Question

Interaction of a PAMP with a TLR triggers transmembrane signal transduction and subsequent
A) clonal expansion.
B) antibody production.
C) complement protein activation.
D) phagocytosis and inflammation.

Accepted Answer

The interaction of a PAMP with a TLR triggers transmembrane signal transduction and subsequent phagocytosis and inflammation. This is because TLRs are a type of pattern recognition receptor (PRR) found on immune cells such as macrophages and dendritic cells that recognize and bind to PAMPs. This triggers a cascade of signals that ultimately leads to the activation of phagocytosis and inflammation, which are important innate immune responses to control infections. Clonal expansion, antibody production, and complement protein activation are all part of the adaptive immune response and do not occur as a direct result of TLR signaling.