Which of the Following is a Likely Target for a Toll-Like

Question

Which of the following is a likely target for a toll-like receptor (TLR)?
A) tumor necrosis factor
B) interleukin IV
C) flagellin
D) insulin

Accepted Answer

Toll-like receptors are specialized proteins in the body that are responsible for recognizing and binding to certain molecules, which are referred to as pathogen-associated molecular patterns (PAMPs). These PAMPs are often found on the surface of infectious agents such as bacteria, viruses, and fungi. Flagellin, the protein that makes up bacterial flagella, is a well-known and common PAMP that can be recognized by several different toll-like receptors. Therefore, choice C (flagellin) is the most likely target for a toll-like receptor. Tumor necrosis factor and interleukin IV are cytokines, which are not likely targets for toll-like receptors. Insulin is a hormone that regulates blood sugar levels and is not a PAMP.