Pattern Recognition Receptors are Most Directly Used

Question

Pattern recognition receptors are most directly used
A) by granulocytes to trigger degranulation.
B) by neutrophils to detect self tissues.
C) by phagocytes to detect pathogens.
D) by B cells to produce antibodies.

Accepted Answer

Pattern recognition receptors (PRRs) are primarily used by phagocytes such as macrophages and dendritic cells to detect and respond to pathogens. PRRs recognize conserved molecular motifs present in pathogens, also known as pathogen-associated molecular patterns (PAMPs). Upon recognition of PAMPs, PRRs activate signaling pathways that lead to the production of cytokines and other inflammatory mediators, as well as the induction of adaptive immune responses. Granulocytes, neutrophils, and B cells may also express PRRs to some extent, but their main function is not directly related to PRR-mediated detection of pathogens.