Cyclic Di-Guanosine Monophosphate is Upregulated as Pseudomonas Aeruginosa Cells Are

Question

Cyclic di-guanosine monophosphate is upregulated as Pseudomonas aeruginosa cells are declining.

Accepted Answer

Cyclic di-guanosine monophosphate (c-di-GMP) is typically upregulated in Pseudomonas aeruginosa to promote biofilm formation and persistence, not during cell decline. It is associated with the transition from a planktonic to a sessile lifestyle, enhancing cell survival and community structure rather than indicating a decline.