________ Prohibits Re-Initiation of Chromosome Replication

Question

________ prohibits re-initiation of chromosome replication.
A) DnaA-ATP
B) SeqA
C) oriC
D) FtsZ

Accepted Answer

SeqA is a protein that binds to hemimethylated DNA (DNA that has been replicated on only one strand), which occurs immediately after replication. This prevents DnaA-ATP from binding and initiating another round of replication at the origin of replication (oriC), thereby inhibiting re-initiation of chromosome replication. FtsZ is involved in bacterial cell division and is not directly related to replication control.