Transcriptional Regulators Bind Most Frequently at the ________ Site of DNA

Question

Transcriptional regulators bind most frequently at the ________ site of DNA.
A) major groove
B) minor groove
C) histone complex
D) primary supercoil

Accepted Answer

Transcriptional regulators most frequently bind at the major groove of DNA because it allows for more specific interactions with the base pairs, facilitating the recognition of specific DNA sequences by these proteins.