When the Sciatic Nerve was Chilled with Iced Ringer's Solution

Question

When the sciatic nerve was chilled with iced Ringer's solution, _.
A) it became inexcitable or required a stimulus much greater than normal to produce a compound action potential
B) the compound action potential was unchanged
C) it became very excitable, generating large compound action potentials to small stimuli

Accepted Answer

When the sciatic nerve is chilled with iced Ringer's solution, it becomes inexcitable or requires a stimulus much greater than normal to produce a compound action potential. This is because cooling slows down the nerve's metabolic processes and ion exchange, making it harder to reach the threshold for action potential generation.