An Amino Acid Substitution to Another of Similar Size and Charge

Question

An amino acid substitution to another of similar size and charge is called a _____ substitution.
A) replicative
B) conservative
C) convergent
D) homologous
E) orthologous

Accepted Answer

Conservative substitutions involve the replacement of an amino acid with another of similar properties (size, charge, hydrophobicity), which often results in minimal functional change to the protein.