What Sequence Identifies a Protein for Translocation Across the ER

Question

What sequence identifies a protein for translocation across the ER?
A) signal sequence
B) Shine-Dalgarno sequence
C) poly-A sequence
D) endoplasmic sequence
E) cargo sequence

Accepted Answer

The signal sequence is a short peptide at the N-terminus of the majority of newly synthesized proteins that are destined for the secretory pathway. It directs the ribosome to the endoplasmic reticulum (ER) for protein translocation.