What Eukaryotic DNA Binding Structure is Similar to the Prokaryotic

Question

What eukaryotic DNA binding structure is similar to the prokaryotic helix-turn-helix?
A) helix-loop-helix
B) leucine zipper
C) zinc finger
D) winged helix-turn-helix
E) homeodomain fold

Accepted Answer

The homeodomain fold in eukaryotes is structurally similar to the prokaryotic helix-turn-helix motif, as both involve a recognition helix that interacts with the major groove of DNA.