The antiviral nucleoside inhibitor zidovudine, used in treating HIV infection, works by

A) fooling reverse transcriptase to incorporate it, causing a chain termination reaction.
B) disabling protease and preventing HIV protein folding.
C) blocking gag and pol genes from transcription.
D) binding directly to reverse transcriptase and allosterically inactivating the enzyme.
E) sterically hindering integrase from cutting into the host nuclear DNA.