Regulation of Complement Destruction of Normal Body Cells is Controlled

Question

Regulation of complement destruction of normal body cells is controlled by
A) CD8, serum factor C3b, and serum albumin.
B) CD58, serum factor H, and decay-accelerating factor.
C) CD4, serum factor Bb, and decay-accelerating factor.
D) MHC I, serum factor C5a, and serum lipoprotein.
E) MHC II, serum albumin, and T regulatory cells.

Accepted Answer

The regulation of complement destruction of normal body cells is controlled by CD58, serum factor H, and decay-accelerating factor. CD58 helps with binding and regulation of complement activation, serum factor H binds to the C3b fragment to inactivate it, and decay-accelerating factor prevents the formation and stability of the C3 convertases.