Positive Selection in T-Cell Education Refers To

Question

Positive selection in T-cell education refers to
A) T-cell receptors that can bind strongly to self MHC proteins.
B) CD8 receptors that can bind strongly to self MHC proteins.
C) T-cell receptors that can bind weakly to self MHC proteins.
D) CD4 that can bind weakly to self MHC proteins.
E) B-cell receptors that bind weakly to T-cell receptors.

Accepted Answer

Positive selection in T-cell education ensures that T-cell receptors can bind weakly to self MHC proteins, allowing T-cells to recognize self-MHC but not strongly enough to initiate an autoimmune response.