A Threshold Dose of Antigen is Best Described as the Dose

Question

A threshold dose of antigen is best described as the dose needed to
A) generate an optimal immune response.
B) activate only a few immune cells.
C) generate only a T-cell response.
D) induce immune complement response.
E) induce immunological tolerance.

Accepted Answer

A threshold dose of antigen is the lowest dose needed to generate an optimal immune response. This is the dose at which enough antigen is present to stimulate a sufficient number of immune cells to produce an effective response, but not so high that it overwhelms the immune system and leads to immune exhaustion or tolerance.