Which Molecules Use 5-Phosphoribosyl-1-Pyrophosphate (PRPP) in Their Biosynthesis

Question

Which molecules use 5-phosphoribosyl-1-pyrophosphate (PRPP) in their biosynthesis?
A) amino acids
B) nucleotides
C) fatty acids
D) tetrapyrrole
E) nonribosomal peptide antibiotics

Accepted Answer

5-phosphoribosyl-1-pyrophosphate (PRPP) is a molecule that is used in the synthesis of nucleotides. It is involved in the de novo synthesis of purine and pyrimidine nucleotides as well as in the salvage pathways of nucleotide synthesis. Amino acids, fatty acids, tetrapyrroles, and nonribosomal peptide antibiotics do not use PRPP in their biosynthesis.