In Anaplerotic Reactions

Question

In anaplerotic reactions
A) intermediates in a pathway are regenerated.
B) nutrients are imported from the environment.
C) molecules targeted for breakdown are salvaged for anabolism.
D) the reactions are thermodynamically impossible.
E) large amounts of ATP are generated.

Accepted Answer

Anaplerotic reactions are metabolic reactions that replenish or regenerate the intermediates of a particular pathway. These reactions are important because they help maintain the steady-state concentration of key metabolites, which can become depleted due to high rates of utilization or catabolism. Examples of anaplerotic reactions include the conversion of pyruvate to oxaloacetate (which can replenish the TCA cycle) and the conversion of phosphoenolpyruvate to oxaloacetate (which can replenish the gluconeogenic pathway). Therefore, choice A is correct.