The Lack of ________ in Some People Makes Them Resistant

Question

The lack of ________ in some people makes them resistant to HIV infection.
A) CD4 receptors on the macrophages
B) CCR5 receptors on the macrophages
C) T4 lymphocytes
D) B-cell receptors
E) nuclear factor kappa beta in the B cells

Accepted Answer

CCR5 receptors on the macrophages are the key binding site for HIV entry into host cells. Individuals with a homozygous deletion of the CCR5 gene are naturally resistant to HIV infection as the virus cannot bind to and infect their immune cells.