The Stringent Response Involves All EXCEPT

Question

The stringent response involves all EXCEPT
A) downregulation of rRNA synthesis.
B) downregulation of tRNA synthesis.
C) ATP.
D) GTP.
E) a lack of change in gene expression.

Accepted Answer

The stringent response is a regulatory mechanism used by bacteria to survive under stressful conditions, such as amino acid starvation. It involves the downregulation of rRNA and tRNA synthesis to conserve resources (choices A and B) and is mediated by the alarmone guanosine tetraphosphate (ppGpp), which affects the synthesis and activity of both ATP and GTP (choices C and D). Therefore, it does not involve a lack of change in gene expression; rather, it significantly alters gene expression to adapt to stress, making choice E incorrect.