Which Form of Control is the LEAST Reversible and MOST

Question

Which form of control is the LEAST reversible and MOST drastic?
A) posttranslational control
B) control of transcription
C) alterations of DNA sequence
D) translational control
E) mRNA stability

Accepted Answer

Alterations of DNA sequence are the least reversible and most drastic form of control because they modify the genetic material itself, and changes to DNA sequence are generally permanent and heritable. On the other hand, posttranslational control, translational control, and mRNA stability can all be quickly reversed or modified, and are not necessarily permanent changes. Control of transcription can be more long-lasting than posttranslational or translational control, but it is still more reversible than alterations to DNA sequence.