The Sliding Clamp is Used to ________ and is Loaded

Question

The sliding clamp is used to ________ and is loaded by ________.
A) open the helix; clamp-loading complex
B) open the helix; DNA polymerase III
C) tether the DNA polymerase to the chromosome; clamp-loading complex
D) tether the DNA polymerase to the chromosome; DNA polymerase I
E) tether the polymerase to the chromosome; DNA primase

Accepted Answer

The sliding clamp functions to tether the DNA polymerase to the chromosome, ensuring high processivity during DNA replication. It is loaded onto the DNA by the clamp-loading complex.