Which of the Following Occurs During the Formation of an Amide

Question

Which of the following occurs during the formation of an amide?
A) A carboxylic acid loses its -OH group and an ammonia or an amine loses its -H atom.
B) A carboxylic acid loses its -OH group and an alcohol loses its -H atom.
C) An alcohol loses its -OH group and an ammonia or an amine loses its -H atom.
D) None of these are correct.

Accepted Answer

During the formation of an amide, a carboxylic acid reacts with an ammonia or an amine to form an amide. This reaction is called amidation. The carboxylic acid loses its -OH group in the form of water, and the ammonia or amine loses its -H atom. Thus, option A is the correct choice. Option B is incorrect because an alcohol cannot react to form an amide. Option C is incorrect because an alcohol cannot react with ammonia or an amine to form an amide. Option D is incorrect because option A is correct.