Which of the Following Enzymes Catalyzes Only the Reactions of Gluconeogenesis

Question

Which of the following enzymes catalyzes only the reactions of gluconeogenesis?
A) hexokinase
B) phosphoglycerate kinase
C) pyruvate kinase
D) pyruvate carboxylase

Accepted Answer

Pyruvate carboxylase is the enzyme responsible for catalyzing the first step of gluconeogenesis, in which pyruvate is converted to oxaloacetate. Hexokinase catalyzes the first step of glycolysis, phosphoglycerate kinase catalyzes the sixth step of glycolysis, and pyruvate kinase catalyzes the final step of glycolysis. Therefore, none of these enzymes catalyze only the reactions of gluconeogenesis.