For the Successful Development of a Vaccine to Be Used

Question

For the successful development of a vaccine to be used against a pathogen, it is necessary that
A) the surface antigens of the pathogen not change.
B) a rearrangement of the B cell receptor antibodies takes place.
C) all of the surface antigens on the pathogen be identified.
D) the pathogen has only one epitope.
E) the MHC molecules are heterozygous.

Accepted Answer

If the surface antigens of a pathogen change, the immune system may not recognize it as the same pathogen and the vaccine may no longer be effective. Therefore, it is necessary that the surface antigens of the pathogen not change for a vaccine to be successful.