The Elongation of the Leading Strand During DNA Synthesis

Question

The elongation of the leading strand during DNA synthesis
A) progresses away from the replication fork.
B) occurs in the 3' → 5' direction.
C) produces Okazaki fragments.
D) depends on the action of DNA polymerase.
E) does not require a template strand.

Accepted Answer

Elongation of the leading strand involves the action of DNA polymerase, which adds nucleotides in the 5' → 3' direction, towards the replication fork.

Note: A, B, and C are incorrect because elongation of the leading strand does not involve Okazaki fragments and progresses in the 5' → 3' direction towards the replication fork (not away from it). E is also incorrect because a template strand is required for DNA synthesis.