An Okazaki Fragment Has Which of the Following Arrangements

Question

An Okazaki fragment has which of the following arrangements?
A) primase, polymerase, ligase
B) 3' RNA nucleotides, DNA nucleotides 5'
C) 5' RNA nucleotides, DNA nucleotides 3'
D) DNA polymerase I, DNA polymerase III
E) 5' DNA to 3'

Accepted Answer

Okazaki fragments are short sequences of DNA nucleotides which are synthesized discontinuously and later linked together by the enzyme DNA ligase to create the lagging strand during DNA replication. They start with a short RNA primer at the 5' end, which is later replaced by DNA nucleotides extending to the 3' end. This arrangement is correctly described in option C.