Which of the Following is Known as a Philadelphia Chromosome

Question

Which of the following is known as a Philadelphia chromosome?
A) a human chromosome 22 that has had a specific translocation
B) a human chromosome 9 that is found only in one type of cancer
C) an animal chromosome found primarily in the mid-Atlantic area of the United States
D) an imprinted chromosome that always comes from the mother
E) a chromosome found not in the nucleus but in mitochondria

Accepted Answer

A Philadelphia chromosome is a human chromosome 22 that has undergone a specific translocation. This creates the abnormal chromosome 22, which is implicated in certain types of leukemia. Choice B is incorrect because a chromosome 9 is not typically associated with the Philadelphia chromosome. Choices C, D, and E are also incorrect as they do not refer to the specific genetic abnormality known as the Philadelphia chromosome.