Which of the Following Might Result in a Human Zygote

Question

Which of the following might result in a human zygote with 45 chromosomes?
A) an error in either egg or sperm meiotic anaphase
B) failure of the egg nucleus to be fertilized by the sperm
C) fertilization of a 23 chromosome human egg by a 22 chromosome sperm of a closely related species
D) an error in the alignment of chromosomes on the metaphase plate
E) lack of chiasmata in prophase I

Accepted Answer

An error in either egg or sperm meiotic anaphase can result in a human zygote with 45 chromosomes. This could happen if one of the homologous chromosomes fails to separate during meiosis, leading to an extra chromosome in the zygote.