Protein Phosphorylation is Commonly Involved with All of the Following

Question

Protein phosphorylation is commonly involved with all of the following except
A) regulation of transcription by extracellular signaling molecules.
B) enzyme activation.
C) activation of G protein-coupled receptors.
D) activation of receptor tyrosine kinases.
E) activation of protein kinase molecules.

Accepted Answer

Protein phosphorylation is not directly involved in the activation of G protein-coupled receptors, which instead involve conformational changes induced by ligand binding. Protein phosphorylation can play a role in downstream signaling pathways activated by G protein-coupled receptors, however.