Which of the following statements regarding enzymes is true?
A) Enzymes increase the rate of a reaction by making the reaction more exergonic. B) Enzymes increase the rate of a reaction by lowering the activation energy barrier. C) Enzymes increase the rate of a reaction by reducing the rate of reverse reactions. D) Enzymes change the equilibrium point of the reactions they catalyze. E) Enzymes make the rate of a reaction independent of substrate concentrations.