Familial Hypercholesterolemia is Characterized by Which of the Following

Question

Familial hypercholesterolemia is characterized by which of the following?
A) defective LDL receptors on the cell membranes
B) poor attachment of the cholesterol to the extracellular matrix of cells
C) a poorly formed lipid bilayer that cannot incorporate cholesterol into cell membranes
D) inhibition of the cholesterol active transport system in red blood cells
E) a general lack of glycolipids in the blood cell membranes

Accepted Answer

Familial hypercholesterolemia is caused by a genetic defect that results in the production of defective LDL receptors on the cell membranes, leading to an inability to properly clear LDL cholesterol from the bloodstream.