The Fact That Tumor Cells Depend, in Many Cases, on Glycolysis

Question

The fact that tumor cells depend, in many cases, on glycolysis may reflect ________.
A)the low metabolic requirements of cancer cells
B)the high oxygen levels the cancer cells usually encounter
C)an inadequate blood supply within the tumor
D)muations in glycolytic enzyme-encoding genes

Accepted Answer

Many tumors grow rapidly and have an inadequate blood supply. This results in limited oxygen availability, which leads to a shift towards anaerobic metabolism, such as glycolysis, to meet the energy demands of the cancer cells. This is known as the Warburg effect.