How Can Cancer Cells Proliferate in the Absence of Blood

Question

How can cancer cells proliferate in the absence of blood serum?
A)Their nuclei depend on these serum growth factors to maintain their structure.
B)The serum inhibits their growth, while it is necessary for normal cells.
C)The cell cycle of cancer cells does not depend on growth-factor from serum.
D)The cell cycle of cancer cells depends on signals transmitted from serum growth-factor receptors located in their cytoplasm.
E)Their mitochondria depend on serum growth factors for their activity.

Accepted Answer

Cancer cells have mutated to bypass the normal regulatory mechanisms that control the cell cycle. They have acquired mutations that allow them to proliferate independent of external growth signals, including those provided by serum growth factors. Therefore, cancer cells do not require serum growth factors to multiply.