Which Type/s of Hypersensitivities is IgG is Involved With

Question

Which type/s of hypersensitivities is IgG is involved with?
A) Anaphylaxis
B) Antibody-mediated
C) Immune complex-mediated
D) Both anaphylaxis and antibody-mediated
E) Both antibody-mediated and immune complex-mediated

Accepted Answer

IgG is involved in both antibody-mediated (Type II) and immune complex-mediated (Type III) hypersensitivities. Type II hypersensitivity occurs when antibodies target antigens on cell surfaces, leading to cell destruction. Type III hypersensitivity involves immune complex formation (antigen-antibody complexes) that deposit in tissues, causing inflammation and tissue damage.