What is the Key Principle of BOLD FMRI

Question

What is the key principle of BOLD fMRI?
A) Active brain areas consume oxygen
B) Communication between distinct hemispheres occurs
C) Cortical regions interact in a feedforward manner
D) Some cortical neurons have myelinated axons

Accepted Answer

The key principle of BOLD (Blood Oxygen Level Dependent) fMRI is that active brain areas consume more oxygen, leading to changes in the local magnetic properties of the blood, which can be detected by the MRI scanner.