In Eukaryotes, Homologous Recombination is Initiated by ________

Question

In eukaryotes, homologous recombination is initiated by ________.
A) Spo11 generating double- stranded DNA breaks
B) Rad51 generating double- stranded DNA breaks
C) p53 generating single- stranded DNA breaks
D) RecA, RecB, and RecC generating single- stranded DNA breaks
E) ATM signaling double- stranded DNA breaks

Accepted Answer

Homologous recombination in eukaryotes is initiated by the enzyme Spo11, which generates double-stranded DNA breaks. This is a critical step in the process of meiotic recombination, allowing for the exchange of genetic material between homologous chromosomes.