How Does the Eukaryotic Ribosomal Small Subunit Recognize the Start

Question

How does the eukaryotic ribosomal small subunit recognize the start codon on the mRNA?
A) It binds an Met- tRNA to the first AUG codon it encounters.
B) It binds an Met- tRNA to the first AUG codon after the Kozak sequence.
C) It performs an ATP hydrolysis within the small subunit once it encounters a Met- tRNA already bound to the AUG.
D) It undergoes a conformational charge that recruits other proteins when it hydrogens bonds to the correct tri- nucleotide sequence.
E) It wraps the mRNA strand to bring initiation enhancer proteins into the vicinity of the start codon.

Accepted Answer

The eukaryotic ribosomal small subunit recognizes the start codon on the mRNA by binding an initiator methionine tRNA (Met-tRNA) to the first AUG codon that is in a favorable context, often following the Kozak sequence. This sequence helps to position the ribosome correctly to initiate translation.