Sympathetic Stimulation Increases All of the Following EXCEPT

Question

Sympathetic stimulation increases all of the following EXCEPT A) Ca²⁺ entry over the L-type Ca²⁺ channel B) Phospholamban phosphorylation C) Ca²⁺ release through RyR2 D) Rate of Ca²⁺ dissociation from TnC E) Ca²⁺ exit over the PMCA

Accepted Answer

Sympathetic stimulation increases calcium entry, phospholamban phosphorylation, calcium release through RyR2, and the rate of calcium dissociation from troponin C, but it does not directly increase calcium exit over the plasma membrane calcium ATPase (PMCA). PMCA activity is more related to the baseline removal of calcium from cells rather than being directly upregulated by sympathetic activity.