“Calcium-Induced Calcium Release” Refers To

Question

“Calcium-induced calcium release” refers to
A) Increased Icaupon beta adrenergic stimulation
B) Release of Ca from the cardiac SR by Ca that enters the cell across the T-tubule
C) Relaxation of cardiac muscle when Ca is removed by the SR SERCA2a pump
D) Increased Ca uptake by SR following contraction
E) Both A and C are correct

Accepted Answer

"Calcium-induced calcium release" specifically refers to the mechanism where calcium entering the cell through the L-type calcium channels (located on the T-tubules) triggers the release of additional calcium from the sarcoplasmic reticulum (SR) into the cytoplasm in cardiac muscle cells. This process is crucial for cardiac muscle contraction.