W Hich of the Following is Characteristic of Large Dense

Question

W hich of the following is characteristic of large dense core synaptic vesicles? A) They contain neurotransmitters m ade at the nerve terminal. B) Their contents are clear in electron micrographs C) They are about 50 nm in diameter D) They fuse with the presynaptic membrane less than 1 ms after an action potential E) They are generally more than 300 nm away from a Ca²⁺ channel

Accepted Answer

Large dense core vesicles are typically located further away from the presynaptic membrane and Ca²⁺ channels, often more than 300 nm away, and are involved in the release of neuropeptides and other modulatory substances.