The Osmotic Gradient in the Outer Medullary Interstitium is Mainly

Question

The osmotic gradient in the outer medullary interstitium is mainly caused by
A) NaCl
B) Urea
C) Glucose
D) KCl
E) proteins

Accepted Answer

The osmotic gradient in the outer medullary interstitium is primarily established by the active transport of NaCl from the thick ascending limb of the loop of Henle.